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Beilstein J. Org. Chem. 2024, 20, 815–822, doi:10.3762/bjoc.20.73
Graphical Abstract
Figure 1: (a) Representative bioactive drimane-type sesquiterpenoids (DMTs). (b) Reported biosynthetic pathwa...
Figure 2: Chemical structures and HPLC analysis. (a) Chemical structures of isolated sesquiterpenes 2–4 from ...
Figure 3: Biosynthesis of drimenol congeners. (a) The cav BGC. (b) Proposed biosynthetic pathway for drimenol...
Figure 4: Substrate scope of CavA. (a) The chemical structures of eight natural products that were used for f...
Beilstein J. Org. Chem. 2022, 18, 881–888, doi:10.3762/bjoc.18.89
Figure 1: (a) The natural pathways (MVA: blue, MEP: green) for producing IPP and DMAPP; (b) the carbon skelet...
Figure 2: Truncated artificial pathways (six steps) to produce terpentetriene and ent-kaurene.
Figure 3: Construction maps of single plasmid expression system and two-plasmid expression system for overpro...
Figure 4: Optimizing the ratios of ISO/DMAA for overproducing terpentetriene (a) and ent-kaurene (b). Red: IS...
Figure 5: (a) Terpentetriene (red) and ent-kaurene (blue) yields supplied with various concentrations of glyc...